Albiflorin, a well-known Chinese herb, is the main ingredient. That has been a significant component of Radix Paeonia. Alba used in treating depressive disorders since antiquity. However, the mechanism behind the antidepressant properties of albiflorin isn’t fully understood.
The root is one of the components of many traditional formulae. Such as Jiaweisinisan and Dang Gui Shao Yao San. Which are prescribed to treat depression-related disorders. One of these ingredients. Monoterpene glycosides like paeoniflorin and albiflorin. Those are typically described as the primary active constituents from the peony. Studies have shown both long- and short-term administration of albiflorin can produce antidepressant-like effects. This is demonstrated by a decrease in the time of immobility in forced-swim tail-suspension tests on mice. The reverse of the chronic stress-induced mild reduction in sucrose consumption in rats. Albiflorin also produces significant antidepressant effects closely connected to hippocampal 5-HT increases.
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Albiflorin is a monoterpene glycoside that is the primary ingredient of Radix paeoniae Alba. That is commonly utilized in herbal remedies across China, Korea, and Japan. Radix paeoniae, Alba is often referred to as a peony. The root of Paeonia lactiflora Pall, a part of the family of Ranunculaceae. Buying research chemicals is ahectic process. But for this purpose many online and trusted stores are available from where you can buy chemicals online.
Albiflorin is a monoterpenoid chemical with the molecular Formula of 23H 28O 11. And a molecular weight of 480.46. The molecular structure of Albiflorin is depicted in Formula (I). It is a naturally active substance derived from the root of Paeonia lactillora Pall. Paeonia veitchii Lynch, and P. Suffrsticosa Andrz in Ranuculaceae plants.
Recent studies in pharmacology suggest that Albiflorin is an analgesic. Anticonvulsant, sedative effects, immunosystem-related benefits. Also smooth-muscle-related effects, anti-inflammatory effects, actions against pathogenic microorganisms. The liver’s protective effects. In clinical terms, Albiflorin is mainly used to treat treatment of Epilepsia and analgesia and rehabilitation from drug addiction. And treatment for vertigo, treatment of arthritis rheumatoid. And treating bacillary dysentery as well as enteritis, treatment of viral hepatitis. The treatment of age-related illnesses as well as the inability to resist the flocculation of barium sulfate and mucus dissolution. The method used to prepare Albiflorin and its use in the production of the medicinal
|Property Name||Property Value||Reference|
|Molecular Weight||480.5||Computed by PubChem 2.1 (PubChem release 2021.05.07)|
|XLogP3-AA||-1||Computed by XLogP3 3.0 (PubChem release 2021.05.07)|
|Hydrogen Bond Donor Count||5||Computed by Cactvs 18.104.22.168 (PubChem release 2021.05.07)|
|Hydrogen Bond Acceptor Count||11||Computed by Cactvs 22.214.171.124 (PubChem release 2021.05.07)|
|Rotatable Bond Count||7||Computed by Cactvs 126.96.36.199 (PubChem release 2021.05.07)|
|Exact Mass||480.16316171||Computed by PubChem 2.1 (PubChem release 2021.05.07)|
|Monoisotopic Mass||480.16316171||Computed by PubChem 2.1 (PubChem release 2021.05.07)|
|Topological Polar Surface Area||172 Å²||Computed by Cactvs 188.8.131.52 (PubChem release 2021.05.07)|
|Heavy Atom Count||34||Computed by PubChem|
|Formal Charge||0||Computed by PubChem|
|Complexity||830||Computed by Cactvs 184.108.40.206 (PubChem release 2021.05.07)|
|Isotope Atom Count||0||Computed by PubChem|
|Defined Atom Stereocenter Count||5||Computed by PubChem|
|Undefined Atom Stereocenter Count||5||Computed by PubChem|
|Defined Bond Stereocenter Count||0||Computed by PubChem|
|Undefined Bond Stereocenter Count||0||Computed by PubChem|
|Covalently-Bonded Unit Count||1||Computed by PubChem|
|Compound Is Canonicalized||Yes||Computed by PubChem (release 2021.05.07)|